Respiratory Disease Models
Our inhalation research platform enables dynamic aerosol delivery via endotracheal, oral, or nasal routes in both small and large animal models. It supports pharmacodynamic, pharmacogenetic, and toxicology studies for respiratory drugs targeting diseases such as asthma, COPD, and pulmonary fibrosis.
List of Diseases and Research Models
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Disease Type
Animal Model / Study
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Expectorant
•Tracheal phenol red excretion model
•Tracheal ciliary movement model -
Cough Relieving
•Model of ammonia inhalation-induced cough
•Model of citrate inhalation-induced cough
•Model of electrical stimulation-induced cough -
Asthma Relieving
•Model of high-fat diet plus OVA-induced obese asthma
•Model of house dust mite-induced asthma
•Model of OVA-induced allergic asthma
•Model of histamine phosphate inhalation-induced asthma -
Pharyngitis
•Model of beta hemolytic streptococcus infection-induced acute pharyngitis
•Model of pharyngeal spray with ammonia-induced acute pharyngitis -
Extracorporeal Trachea, Bronchus and Lung Tests
•Model of acetylcholine/histamine-induced isolated tracheal smooth muscle contraction
•Lung bronchial perfusion test -
Chronic Pulmonary Disease
•Model of cold plus SO2-induced chronic obstructive pulmonary disease (lung qi deficiency)
•Model of smoking plus LPS-induced chronic obstructive pulmonary disease (lung qi deficiency)
•Model of bleomycin-induced pulmonary fibrosis
