Cardiovascular & Cerebrovascular Disease Models
Cardiovascular and cerebrovascular diseases—including hypertension, heart failure, stroke, and atherosclerosis—are leading global health challenges. Animal models play a vital role in evaluating new treatments, from lipid-lowering drugs like PCSK9 inhibitors (e.g., evolocumab) in ApoE-/- mice to stroke therapies tested in MCAO models. Our validated models enable reliable preclinical assessment to support the development of innovative therapies in this critical field.
List of Diseases and Research Models
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Disease Type
Animal Model / Study
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Hypertension, Chronic Heart Failure (CHF)
•Spontaneous hypertension (with CHF) model
•Model of coronary artery ligation-induced CHF
•Model of Iso-induced CHF
•Spontaneous hypertension (SHR) model
•Model of renal hypertension with abdominal aortic coarctation
•Echocardiography image enhancement test -
Blood Stasis, Thrombosis, Coagulation
•Model of dextran-induced blood stasis
•Model of Iso-induced blood stasis
•Arteriovenous bypass thrombosis
•Model of carrageenin-induced tail vein thrombosis
•Model of ADP-induced platelet aggregation
•Normal animal
