Cell Therapy Products
We support preclinical development of both genetically modified and non-genetically modified cellular therapies through advanced in vitro and in vivo platforms. Equipped with tools such as in vivo imaging, flow cytometry, ELISPOT, and immunofluorescence, we conduct comprehensive safety and functional studies on CAR-T, CAR-NK, TCR-T cells, stem cells, and other immune cell types. These models are vital in evaluating efficacy and safety of cell therapies targeting cancer and immune disorders.
Cell Therapy Study Content
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Cellular Product Testing
Testing Items
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Cell identification
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Survival rate and proliferation capacity
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Purity and homogeneity
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Sterility testing and mycoplasma testing
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Endotoxin testing
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Detection of intracellular and exogenous factors
• In vitro blood adsorption/hemagglutination assay with different passaged cell culture media
• Intracerebral and intraperitoneal inoculation in mice
• Intracerebral and intraperitoneal inoculation in suckling mice
• Chicken embryo yolk sac cavity inoculation
• Chicken embryo urinary bladder cavity inoculation and urinary bladder fluid hemagglutination test
• Guinea pig intraperitoneal inoculation
• Subcutaneous/intracutaneous inoculation in rabbits -
Abnormal immune response
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Tumorigenicity testing
• In vivo tumorigenicity test in nude mice
• Tumorigenicity assay for different generations of cells
• Soft agar clone formation test
• Telomerase activity test
• Karyotype analysis -
Biological effectiveness testing
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Detection of residues of other added components and non-functional heterogeneous cell populations in the culture system
Research Projects
Accomplished
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3 +
3 Immuno- cell therapy (DC, CIK, CTL)
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6 +
6 CAR-T and TCR-T projects
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6
6 Stem cell and iPSC projects and devices
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15
15 Investigational study on new cell therapy targets
